TMX2-CTNND1

Across TCGA patient cohorts, TMX2-CTNND1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,991 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMX2-CTNND1-associated GO terms across cancer lineages are Regulation of macroautophagy, Negative regulation of macroautophagy, and Circadian regulation of gene expression. Each is linked with TMX2-CTNND1 in more than 24 cancer types. Because this analysis shows association rather than direction, both TMX2-CTNND1-to-partner and partner-to-TMX2-CTNND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macroautophagy grouped by TMX2-CTNND1-low versus TMX2-CTNND1-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMX2-CTNND1→partner) and Y-score (partner→TMX2-CTNND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Regulation of macroautophagy →	+0.046	+0.230	<.001	<.001	3	25
GBM	Negative regulation of macroautophagy →	+0.045	+0.600	<.001	<.001	3	25
THYM	Circadian regulation of gene expression →	+0.053	+0.151	<.001	<.001	3	25
THYM	Regulation of autophagosome assembly →	+0.052	+0.194	<.001	<.001	3	24
THYM	Response to L-leucine →	+0.064	+0.209	<.001	<.001	3	24
THYM	Regulation of vacuole organization →	+0.058	+0.215	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,991 associations by consensus.

Regulation of macroautophagy by TMX2-CTNND1 expression — THYM

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