TMX2-CTNND1

Across TCGA pan-cancer cohorts, TMX2-CTNND1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated TMX2-CTNND1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher TMX2-CTNND1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TMX2-CTNND1 expression acts as an unfavorable survival marker, although some lineages such as UCS and SKCM show a favorable association.

UCS, READ, and ACC are the cancer types where TMX2-CTNND1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	II,III,IV	0.700	0.251	.002	66	view →
READ	DFS	Tertile	II,III,IV	0.235	0.794	<.001	51	view →
ACC	DFS	Quartile	All	0.301	0.654	.001	47	view →
SKCM	OS	Quartile	III,IV	0.675	0.369	.007	39	view →
CHOL	DFS	Tertile	II,III,IV	0.032	0.477	<.001	36	view →
THCA	OS	Tertile	II,III,IV	0.701	0.917	.012	18	view →
LGG	DFS	Median	All	0.889	0.757	<.001	18	view →
ESCA	OS	Tertile	III,IV	0.398	0.627	.015	15	view →
KIRC	DFS	Median	All	0.701	0.564	.006	14	view →
COAD	DFS	Tertile	IV	0.315	0.524	.031	12	view →
MESO	OS	Tertile	IV	0.266	0.608	.044	9	view →
LIHC	DFS	Tertile	III,IV	0.130	0.358	.007	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

TMX2-CTNND1–UCS (OS)

Open the UCS breakdown →