Across TCGA patient cohorts, TMSB4X mutation is significantly associated with the RNA expression of many other genes, with 413 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMSB4X-associated genes across cancer lineages are CST8, POU4F2, and OR52L1. Each is linked with TMSB4X in more than 1 cancer types. Because this analysis shows association rather than direction, both TMSB4X-to-partner and partner-to-TMSB4X results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMSB4X→partner) and Y-score (partner→TMSB4X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	CST8 →	+0.105	+3.655	.003	.005	3	1
DLBC	POU4F2 →	+0.098	+4.078	.004	.003	3	1
DLBC	OR52L1 →	+0.279	+3.655	.001	.005	3	1
DLBC	MIR365A →	+0.395	+3.887	.004	.005	3	1
DLBC	RN7SKP228 →	+0.171	+3.655	<.001	.005	3	1
DLBC	TXNP2 →	+0.161	+3.655	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 413 associations by consensus.

Exploration

TMSB4X survival (RNA) · tumor vs normal (RNA) · all TMSB4X data types