Q-omics provides the consensus-scored MIR365A profile across patient tissues and cancer cell-line models. MIR365A expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, MIR365A is differentially expressed in 4, with the highest sampling consensus in LUSC. Additionally, MIR365A RNA expression shows 6,188 significant protein co-abundance associations, with the highest sampling consensus in HNSC. Together, these results highlight UCEC, LUSC, and HNSC as cancer lineages where MIR365A shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR365A — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR365A survival associations across molecular data types. MIR365A RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR365A RNA expression–survival associations across cancer types. High MIR365A expression shows unfavorable associations in UCEC, MESO, THYM, CESC and LGG, but favorable associations in LUSC. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for MIR365A RNA expression.
This table summarizes MIR365A tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR365A. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR365A shows lower tumor expression in THCA and KIRC and higher tumor expression in LUSC and LIHC. The LUSC box plot shows higher MIR365A RNA expression in tumor versus normal tissue (log2 FC = +0.309, t-test p < 0.001).
This table shows molecular features associated with MIR365A in patient tissues and cancer cell lines. In patient samples, MIR365A shows the broadest associations at the RNA and protein expression levels, with HNSC recurring as the lineage with the largest associated feature set.
