Across TCGA pan-cancer cohorts, MIR365A RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR365A’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MIR365A RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR365A is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

LUSC, LIHC, and THCA are the cancer types where MIR365A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR365A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+0.309	<.001	4	view →
LIHC	All	II,III,IV	+0.139	.027	3	view →
THCA	All	II,III,IV	−0.111	.043	1	view →
KIRC	Female	All	−0.103	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MIR365A RNA expression & survival · all MIR365A data types