TMPRSS11E

Across TCGA patient cohorts, TMPRSS11E RNA expression is significantly associated with the protein abundance of many other proteins, with 7,061 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMPRSS11E-associated proteins across cancer lineages are SCEL_S312, KRT80, and PPL. Each is linked with TMPRSS11E in more than 4 cancer types. Because this analysis shows association rather than direction, both TMPRSS11E-to-partner and partner-to-TMPRSS11E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMPRSS11E versus SCEL_S312 in LUAD, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS11E→partner) and Y-score (partner→TMPRSS11E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SCEL_S312 →	+1.325	+1.858	<.001	.001	3	5
HNSC	KRT80 →	+0.864	+1.632	.006	.003	3	5
PDAC	PPL →	+0.691	+1.148	<.001	<.001	3	4
LSCC	PPL_S830 →	+0.898	+1.779	.002	.002	3	4
UCEC	PKP1 →	+1.352	+1.598	<.001	<.001	3	4
PDAC	RPTN →	+1.866	+1.942	.009	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,061 associations by consensus.

TMPRSS11E vs SCEL_S312 — LUAD

Explore this scatter interactively →