TMPRSS11E

Across TCGA patient cohorts, TMPRSS11E protein abundance is significantly associated with the RNA expression of many other genes, with 3,644 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TMPRSS11E-associated genes across cancer lineages are IL36RN, TTLL12, and FERMT1. Each is linked with TMPRSS11E in more than 2 cancer types. Because this analysis shows association rather than direction, both TMPRSS11E-to-partner and partner-to-TMPRSS11E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMPRSS11E versus IL36RN in HNSC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS11E→partner) and Y-score (partner→TMPRSS11E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IL36RN →	+1.892	+0.719	<.001	<.001	3	3
HNSC	TTLL12 →	+0.839	+0.747	<.001	.001	3	2
LSCC	FERMT1 →	+1.559	+1.409	<.001	<.001	3	2
HNSC	TGM5 →	+1.005	+0.738	.001	.001	3	2
LSCC	RHOV →	+1.118	+0.929	<.001	.002	3	2
HNSC	PLIN3 →	+1.128	+0.653	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,644 associations by consensus.

TMPRSS11E vs IL36RN — HNSC

Explore this scatter interactively →