TMPRSS11D

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TMPRSS11D protein abundance is significantly associated with the RNA expression of many other genes, with 6,944 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TMPRSS11D-associated genes across cancer lineages are YPEL1, NOL4, and KLF5. Each is linked with TMPRSS11D in more than 1 cancer types. Because this analysis shows association rather than direction, both TMPRSS11D-to-partner and partner-to-TMPRSS11D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMPRSS11D versus YPEL1 in HNSC, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMPRSS11D→partner) and Y-score (partner→TMPRSS11D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCYPEL1 →-0.739-1.052<.001<.00132
HNSCNOL4 →-0.341-0.604.006.00132
LSCCKLF5 →+1.302+1.313<.001<.00132
LSCCSTARD3NL →-0.543-1.002<.001.00132
HNSCN4BP1 →+0.432+0.647<.001.00132
LSCCQPRT →-1.241-1.122<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,944 associations by consensus.

TMPRSS11D vs YPEL1 — HNSC

Per-sample scatter of TMPRSS11D vs YPEL1 in HNSC (Pearson r = -0.47).

Explore this scatter interactively →

Exploration