TMEM95

Across TCGA patient cohorts, TMEM95 mutation is significantly associated with the RNA expression of many other genes, with 164 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible TMEM95-associated genes across cancer lineages are SUMO2P14, LINC01796, and RNA5SP226. Each is linked with TMEM95 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM95-to-partner and partner-to-TMEM95 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SUMO2P14 grouped by TMEM95-low versus TMEM95-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM95→partner) and Y-score (partner→TMEM95) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SUMO2P14 →	+0.439	+3.925	.007	<.001	3	2
UCEC	LINC01796 →	+0.189	+3.492	.009	.003	3	2
UCEC	RNA5SP226 →	+1.499	+3.568	<.001	.006	3	2
UCEC	RNU6ATAC29P →	+0.527	+3.579	<.001	.002	3	2
UCEC	RNA5SP182 →	+0.803	+4.555	<.001	.005	3	2
SKCM	RNA5SP91 →	+0.348	+5.037	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 164 associations by consensus.

SUMO2P14 by TMEM95 expression — UCEC

Explore this box plot interactively →