TMEM95

Across TCGA pan-cancer cohorts, TMEM95 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated TMEM95 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TMEM95 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TMEM95 expression acts as an unfavorable survival marker, although some lineages such as STAD and PAAD show a favorable association.

HNSC, OV, and READ are the cancer types where TMEM95 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.608	0.757	<.001	50	view →
OV	DFS	Tertile	III,IV	0.486	0.585	.008	32	view →
READ	OS	Tertile	III,IV	0.786	0.931	.021	24	view →
STAD	OS	Tertile	III,IV	0.492	0.280	.014	22	view →
THCA	OS	Quartile	All	0.945	0.985	.007	19	view →
KIRC	DFS	Quartile	IV	0.323	0.664	.001	14	view →
LGG	OS	Quartile	All	0.390	0.531	.013	13	view →
PAAD	DFS	Median	II,III,IV	0.595	0.385	.011	12	view →
COAD	DFS	Tertile	IV	0.858	0.358	.032	9	view →
CHOL	DFS	Quartile	III,IV	1.000	0.174	.040	8	view →
CESC	OS	Median	IV	0.546	0.187	.038	6	view →
GBM	OS	Median	All	0.215	0.303	.019	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

TMEM95–HNSC (OS)

Open the HNSC breakdown →