TMEM95

Across TCGA pan-cancer cohorts, TMEM95 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of TMEM95’s most consistent transcriptional readouts.

The strongest signal is observed in rectum adenocarcinoma (READ), where TMEM95 RNA is repressed in tumor relative to normal tissue. In most cancer types TMEM95 is over-expressed in tumor, although a few such as READ and THCA show the opposite, repressed pattern.

READ, THCA, and KICH are the cancer types where TMEM95 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TMEM95 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
READ	All	All	−0.100	.001	7	view →
THCA	All	All	−0.078	.004	5	view →
KICH	All	All	−0.021	.013	3	view →
LUAD	Male	All	+0.051	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

TMEM95–READ

Open the READ breakdown →