TMEM9

Across TCGA cell cohorts, TMEM9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,735 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TMEM9-associated GO terms across cancer lineages are Nucleoside triphosphate metabolic process, Nucleoside triphosphate biosynthetic process, and Growth hormone secretion. Each is linked with TMEM9 in more than 11 cancer types. Because this analysis shows association rather than direction, both TMEM9-to-partner and partner-to-TMEM9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside triphosphate metabolic process grouped by TMEM9-low versus TMEM9-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM9→partner) and Y-score (partner→TMEM9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleoside triphosphate metabolic process →	+0.091	+0.719	<.001	.007	3	12
BONE	Nucleoside triphosphate biosynthetic process →	+0.098	+0.877	.001	.001	3	11
STOMACH	Growth hormone secretion →	+0.145	+1.564	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Oxidative phosphorylation →	+0.074	+0.665	.001	.005	3	11
UPPER_AERODIGESTIVE_TRACT	Phospholipid biosynthetic process →	+0.055	+1.051	<.001	<.001	3	10
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.092	+2.093	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,735 associations by consensus.

Nucleoside triphosphate metabolic process by TMEM9 expression — BONE

Explore this box plot interactively →