Across TCGA patient cohorts, TMEM88B protein abundance is significantly associated with the RNA expression of many other genes, with 1,902 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM88B-associated genes across cancer lineages are TXNL4AP1, OR2W3, and KCNV2. Each is linked with TMEM88B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM88B-to-partner and partner-to-TMEM88B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM88B→partner) and Y-score (partner→TMEM88B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TXNL4AP1 →	+0.724	+0.638	.006	<.001	3	2
HNSC	OR2W3 →	+0.512	+0.625	.009	.004	3	2
HNSC	KCNV2 →	-0.735	-0.727	.002	.003	3	1
HNSC	RNA5SP110 →	+0.402	+0.619	.007	.006	3	1
HNSC	RNU4-61P →	+0.914	+0.550	.009	.004	3	1
HNSC	RBMY2JP →	+0.856	+0.560	.006	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,902 associations by consensus.

Exploration

TMEM88B survival (RNA) · tumor vs normal (RNA) · all TMEM88B data types