Across TCGA cell cohorts, TMEM88B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,036 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TMEM88B-associated GO terms across cancer lineages are Response to cobalt ion, Negative regulation of transcription by RNA polymerase III, and Regulation of cell fate commitment. Each is linked with TMEM88B in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM88B-to-partner and partner-to-TMEM88B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM88B→partner) and Y-score (partner→TMEM88B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Response to cobalt ion →	+0.073	+0.658	.002	.006	3	6
OESOPHAGUS	Negative regulation of transcription by RNA polymerase III →	+0.150	+0.751	<.001	.006	2	6
SOFT_TISSUE	Regulation of cell fate commitment →	+0.105	+0.613	<.001	.002	3	5
SOFT_TISSUE	Regulation of cholesterol efflux →	+0.088	+0.772	<.001	.006	3	5
SOFT_TISSUE	Positive regulation of dendrite morphogenesis →	+0.071	+0.962	<.001	.001	2	6
LUNG_SCLC	Calcium-independent cell-matrix adhesion →	+0.171	+0.960	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,036 associations by consensus.

Exploration

TMEM88B survival (RNA) · tumor vs normal (RNA) · all TMEM88B data types