TMEM65

Across TCGA patient cohorts, TMEM65 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,171 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible TMEM65-associated GO terms across cancer lineages are miRNA processing, Establishment of cell polarity, and Ribosome-associated ubiquitin-dependent protein catabolic process. Each is linked with TMEM65 in more than 30 cancer types. Because this analysis shows association rather than direction, both TMEM65-to-partner and partner-to-TMEM65 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, miRNA processing grouped by TMEM65-low versus TMEM65-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM65→partner) and Y-score (partner→TMEM65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	miRNA processing →	+0.045	+0.925	<.001	<.001	3	31
THYM	Establishment of cell polarity →	+0.040	+0.571	<.001	<.001	3	31
DLBC	Ribosome-associated ubiquitin-dependent protein catabolic process →	+0.091	+0.915	<.001	<.001	3	31
UVM	Protein modification by small protein removal →	+0.053	+1.245	<.001	<.001	3	31
UVM	mRNA alternative polyadenylation →	+0.084	+1.289	<.001	<.001	3	31
DLBC	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.070	+0.897	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,171 associations by consensus.

miRNA processing by TMEM65 expression — UCS

Explore this box plot interactively →