TMEM61

Across TCGA cell cohorts, TMEM61 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,089 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible TMEM61-associated GO terms across cancer lineages are Cellular response to indole-3-methanol, Regulation of endoplasmic reticulum unfolded protein response, and Desmosome assembly. Each is linked with TMEM61 in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM61-to-partner and partner-to-TMEM61 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to indole-3-methanol grouped by TMEM61-low versus TMEM61-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM61→partner) and Y-score (partner→TMEM61) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Cellular response to indole-3-methanol →	+0.265	+1.221	<.001	<.001	3	9
PANCREAS	Regulation of endoplasmic reticulum unfolded protein response →	+0.106	+0.749	<.001	.004	3	8
OVARY	Desmosome assembly →	+0.239	+0.612	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.100	-0.756	.004	.009	3	7
OVARY	Cilium-dependent cell motility →	-0.058	-0.653	.001	.002	3	7
KIDNEY	Cilium movement involved in cell motility →	-0.063	-0.203	<.001	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,089 associations by consensus.

Cellular response to indole-3-methanol by TMEM61 expression — PANCREAS

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