TMEM51-AS1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TMEM51-AS1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM51-AS1-associated genes across cancer lineages are SNORD115-9 and RNA5SP376. Each is linked with TMEM51-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM51-AS1-to-partner and partner-to-TMEM51-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD115-9 grouped by TMEM51-AS1-low versus TMEM51-AS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM51-AS1→partner) and Y-score (partner→TMEM51-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSNORD115-9 →+0.612+8.066<.001.00731
UCECRNA5SP376 →+0.556+8.066<.001.00731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SNORD115-9 by TMEM51-AS1 expression — UCEC

Box plot of SNORD115-9 in TMEM51-AS1-low vs TMEM51-AS1-high samples in UCEC.

Explore this box plot interactively →

Exploration