TMEM45A

Across TCGA cell cohorts, TMEM45A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,767 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMEM45A-associated GO terms across cancer lineages are Maintenance of protein location in cell, Positive regulation of protein exit from endoplasmic reticulum, and Maintenance of protein location. Each is linked with TMEM45A in more than 13 cancer types. Because this analysis shows association rather than direction, both TMEM45A-to-partner and partner-to-TMEM45A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of protein location in cell grouped by TMEM45A-low versus TMEM45A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM45A→partner) and Y-score (partner→TMEM45A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Maintenance of protein location in cell →	+0.123	+1.630	<.001	.002	3	14
BONE	Positive regulation of protein exit from endoplasmic reticulum →	+0.151	+1.886	<.001	<.001	3	13
BONE	Maintenance of protein location →	+0.121	+1.610	<.001	.002	3	13
BONE	Regulation of protein exit from endoplasmic reticulum →	+0.139	+1.605	<.001	<.001	3	12
BONE	Maintenance of protein localization in organelle →	+0.124	+1.720	.001	.002	3	12
BONE	Bleb assembly →	+0.289	+1.705	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,767 associations by consensus.

Maintenance of protein location in cell by TMEM45A expression — BONE

Explore this box plot interactively →