Across TCGA cell cohorts, TMEM255B mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM255B-associated genes across cancer lineages are OR13C3, OR7G2, and AVP. Each is linked with TMEM255B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM255B-to-partner and partner-to-TMEM255B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM255B→partner) and Y-score (partner→TMEM255B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR13C3 →	+0.022	+4.887	<.001	.009	3	2
LUNG_NSCLC_LUAD	OR7G2 →	+0.022	+4.887	<.001	.009	3	1
LARGE_INTESTINE	AVP →	+0.048	+3.217	<.001	.006	3	1
LARGE_INTESTINE	MAGEB4 →	+0.014	+4.000	<.001	<.001	3	1
LARGE_INTESTINE	H1-1 →	+0.077	+3.376	<.001	.002	3	1
LARGE_INTESTINE	SPACA5 →	+0.072	+2.878	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

TMEM255B survival (RNA) · tumor vs normal (RNA) · all TMEM255B data types