TMEM254

Across TCGA patient cohorts, TMEM254 protein abundance is significantly associated with the RNA expression of many other genes, with 8,329 significant associations in total. COAD shows the largest number of these associations.

The most reproducible TMEM254-associated genes across cancer lineages are NUDT13, AP1G1, and FAM71F2. Each is linked with TMEM254 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM254-to-partner and partner-to-TMEM254 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM254 versus NUDT13 in OV, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM254→partner) and Y-score (partner→TMEM254) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NUDT13 →	+0.666	+0.632	<.001	<.001	3	2
OV	AP1G1 →	+0.805	+0.730	.004	.002	3	2
OV	FAM71F2 →	+1.160	+0.569	<.001	.004	3	2
OV	RPL21P1 →	-2.042	-0.659	<.001	.003	3	2
OV	RPS11P5 →	-1.915	-0.658	<.001	.002	3	2
OV	NSA2P1 →	-1.779	-0.608	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,329 associations by consensus.

TMEM254 vs NUDT13 — OV

Explore this scatter interactively →