TMEM254

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TMEM254 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,001 significant associations in total. COAD shows the largest number of these associations.

The most reproducible TMEM254-associated proteins across cancer lineages are TMEM94_S225, TRIO_S2499, and DENND4C_S989. Each is linked with TMEM254 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM254-to-partner and partner-to-TMEM254 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM254 versus TMEM94_S225 in OV, with a Pearson correlation of -0.67.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM254→partner) and Y-score (partner→TMEM254) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVTMEM94_S225 →-1.822-1.347<.001<.00132
OVTRIO_S2499 →-2.386-1.308.001<.00132
LUADDENND4C_S989 →-1.127-0.531<.001<.00132
OVDMXL1_S1970 →+1.037+1.394<.001<.00132
OVELOF1 →-1.541-0.855<.001<.00132
OVFOXC1_S320 →-1.337-0.884<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,001 associations by consensus.

TMEM254 vs TMEM94_S225 — OV

Per-sample scatter of TMEM254 vs TMEM94_S225 in OV (Pearson r = -0.67).

Explore this scatter interactively →

Exploration