TMEM254

Across TCGA cell cohorts, TMEM254 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,885 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMEM254-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Cilium-dependent cell motility, and Vesicle targeting, rough ER to cis-Golgi. Each is linked with TMEM254 in more than 11 cancer types. Because this analysis shows association rather than direction, both TMEM254-to-partner and partner-to-TMEM254 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by TMEM254-low versus TMEM254-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM254→partner) and Y-score (partner→TMEM254) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.085	-0.884	.001	.005	3	12
OESOPHAGUS	Cilium-dependent cell motility →	-0.085	-0.884	.001	.005	3	12
BLOOD_Myeloma	Vesicle targeting, rough ER to cis-Golgi →	+0.079	+0.927	.004	.003	2	12
BLOOD_Lymphoma	Protein catabolic process at synapse →	+0.108	+1.046	<.001	<.001	3	10
BLOOD_Lymphoma	Protein catabolic process at postsynapse →	+0.108	+1.046	<.001	<.001	3	10
BLOOD_Myeloma	Phospholipid biosynthetic process →	+0.030	+1.133	.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,885 associations by consensus.

Cilium or flagellum-dependent cell motility by TMEM254 expression — OESOPHAGUS

Explore this box plot interactively →