TMEM238

Across TCGA patient cohorts, TMEM238 protein abundance is significantly associated with the RNA expression of many other genes, with 7,228 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM238-associated genes across cancer lineages are ATP8B1, FADS3, and DUXAP9. Each is linked with TMEM238 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM238-to-partner and partner-to-TMEM238 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM238 versus ATP8B1 in OV, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM238→partner) and Y-score (partner→TMEM238) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ATP8B1 →	+1.046	+0.520	<.001	<.001	3	5
HNSC	FADS3 →	-0.974	-0.697	<.001	<.001	3	4
LSCC	DUXAP9 →	-0.612	-0.318	<.001	.003	3	4
BRCA	TTC39A-AS1 →	+0.769	+0.542	<.001	<.001	3	4
COAD	RUBCNL →	-1.252	-0.207	<.001	.006	3	3
HNSC	DSE →	-0.589	-0.505	.003	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,228 associations by consensus.

TMEM238 vs ATP8B1 — OV

Explore this scatter interactively →