TMEM229A

Across TCGA patient cohorts, TMEM229A mutation is significantly associated with the RNA expression of many other genes, with 666 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM229A-associated genes across cancer lineages are RN7SL66P, RNU6-1213P, and SLC1A2. Each is linked with TMEM229A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM229A-to-partner and partner-to-TMEM229A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL66P grouped by TMEM229A-low versus TMEM229A-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM229A→partner) and Y-score (partner→TMEM229A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL66P →	+0.233	+5.288	<.001	.006	3	2
UCEC	RNU6-1213P →	+0.297	+4.292	<.001	<.001	3	2
SCLC	SLC1A2 →	+1.611	+4.329	<.001	.006	3	1
SCLC	LMX1A →	+1.226	+4.169	<.001	.008	3	1
SCLC	NCR2 →	+0.259	+4.502	.004	.004	3	1
BRCA	RNU6-1313P →	+0.582	+5.610	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 666 associations by consensus.

RN7SL66P by TMEM229A expression — BRCA

Explore this box plot interactively →