TMEM204

Across TCGA patient cohorts, TMEM204 protein abundance is significantly associated with the RNA expression of many other genes, with 408 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TMEM204-associated genes across cancer lineages are LGALS1, SYNDIG1, and CACNA1F. Each is linked with TMEM204 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM204-to-partner and partner-to-TMEM204 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM204 versus LGALS1 in PDAC, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM204→partner) and Y-score (partner→TMEM204) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	LGALS1 →	+1.365	+0.979	.001	<.001	3	1
PDAC	SYNDIG1 →	+1.704	+1.056	<.001	<.001	3	1
PDAC	CACNA1F →	-0.226	-0.827	.008	<.001	3	1
PDAC	SRPX2 →	+1.039	+0.830	.006	.003	3	1
PDAC	PDGFRL →	+1.331	+0.692	<.001	.002	3	1
PDAC	PCOLCE →	+1.200	+0.773	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 408 associations by consensus.

TMEM204 vs LGALS1 — PDAC

Explore this scatter interactively →