TMEM204

Across TCGA cell cohorts, TMEM204 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,283 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM204-associated GO terms across cancer lineages are mRNA transport, Nuclear export, and Signal transduction in response to DNA damage. Each is linked with TMEM204 in more than 7 cancer types. Because this analysis shows association rather than direction, both TMEM204-to-partner and partner-to-TMEM204 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA transport grouped by TMEM204-low versus TMEM204-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM204→partner) and Y-score (partner→TMEM204) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	mRNA transport →	+0.059	+0.812	<.001	.005	2	8
SOFT_TISSUE	Nuclear export →	+0.078	+1.422	<.001	.005	3	5
SOFT_TISSUE	Signal transduction in response to DNA damage →	+0.054	+1.060	<.001	.004	3	5
STOMACH	Regulation of alternative mRNA splicing, via spliceosome →	+0.086	+0.397	.006	.008	2	6
BLOOD_Leukemia	Protein localization to cytoplasmic stress granule →	+0.088	+0.850	<.001	.006	3	5
BLOOD_Leukemia	Positive regulation of DNA repair →	+0.038	+0.733	<.001	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,283 associations by consensus.

mRNA transport by TMEM204 expression — BLOOD_Leukemia

Explore this box plot interactively →