TMEM200A

Across TCGA cell cohorts, TMEM200A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,366 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TMEM200A-associated GO terms across cancer lineages are Positive regulation of cytoskeleton organization, Establishment of epithelial cell apical/basal polarity, and Establishment of apical/basal cell polarity. Each is linked with TMEM200A in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM200A-to-partner and partner-to-TMEM200A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytoskeleton organization grouped by TMEM200A-low versus TMEM200A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM200A→partner) and Y-score (partner→TMEM200A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of cytoskeleton organization →	+0.043	+0.484	.001	.007	3	9
SKIN	Establishment of epithelial cell apical/basal polarity →	+0.098	+2.310	<.001	<.001	3	9
SOFT_TISSUE	Establishment of apical/basal cell polarity →	+0.110	+1.228	<.001	.007	2	9
SKIN	Positive regulation of cell-substrate junction organization →	+0.072	+1.400	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Positive regulation of tumor necrosis factor superfamily cytokine production →	+0.121	+2.001	.004	.002	3	8
SOFT_TISSUE	Positive regulation of extrinsic apoptotic signaling pathway →	+0.112	+2.138	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,366 associations by consensus.

Positive regulation of cytoskeleton organization by TMEM200A expression — BREAST

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