TMEM200A

Across TCGA cell cohorts, TMEM200A mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TMEM200A-associated genes across cancer lineages are RSPH6A, LACTBL1, and ACER1. Each is linked with TMEM200A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM200A-to-partner and partner-to-TMEM200A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RSPH6A grouped by TMEM200A-low versus TMEM200A-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM200A→partner) and Y-score (partner→TMEM200A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RSPH6A →	+0.017	+4.011	.001	.009	3	2
BLOOD_Lymphoma	LACTBL1 →	+0.007	+4.058	<.001	.009	3	2
LARGE_INTESTINE	ACER1 →	+0.092	+3.823	.001	.006	3	1
LARGE_INTESTINE	RAX2 →	+0.077	+3.196	<.001	.007	3	1
LARGE_INTESTINE	OR12D2 →	+0.061	+3.882	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR4N5 →	+0.022	+4.662	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

RSPH6A by TMEM200A expression — SKIN

Explore this box plot interactively →