TMEM192

Across TCGA patient cohorts, TMEM192 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,110 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM192-associated proteins across cancer lineages are ARFIP1, TMEM192_S230, and VPS35L. Each is linked with TMEM192 in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM192-to-partner and partner-to-TMEM192 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM192 versus ARFIP1 in BRCA, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM192→partner) and Y-score (partner→TMEM192) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARFIP1 →	+0.361	+0.597	<.001	<.001	3	7
HNSC	TMEM192_S230 →	+0.882	+0.465	<.001	<.001	3	5
OV	VPS35L →	+0.311	+0.513	<.001	.008	3	5
CCRCC	CRYZ →	+0.365	+0.487	<.001	<.001	3	5
LUAD	RBM47 →	+0.331	+0.459	<.001	<.001	3	4
LUAD	PHYH →	+0.392	+0.258	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,110 associations by consensus.

TMEM192 vs ARFIP1 — BRCA

Explore this scatter interactively →