TMEM183A

Across TCGA patient cohorts, TMEM183A mutation is significantly associated with the RNA expression of many other genes, with 1,694 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM183A-associated genes across cancer lineages are RNY1P8, LINC01784, and YTHDF3-AS1. Each is linked with TMEM183A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM183A-to-partner and partner-to-TMEM183A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNY1P8 grouped by TMEM183A-low versus TMEM183A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM183A→partner) and Y-score (partner→TMEM183A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNY1P8 →	+0.375	+3.453	<.001	.003	3	2
LUSC	LINC01784 →	+0.179	+7.924	<.001	.008	3	2
UCEC	YTHDF3-AS1 →	+0.788	+2.754	<.001	.003	3	1
UCEC	BNIP3P4 →	+0.082	+3.025	<.001	.002	3	1
UCEC	CCL5 →	+1.319	+2.721	.001	.003	3	1
UCEC	WASL-DT →	+0.602	+3.370	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,694 associations by consensus.

RNY1P8 by TMEM183A expression — UCEC

Explore this box plot interactively →