TMEM183A

Across TCGA cell cohorts, TMEM183A mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TMEM183A-associated genes across cancer lineages are S100A7A, CFHR2, and SLC7A13. Each is linked with TMEM183A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM183A-to-partner and partner-to-TMEM183A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, S100A7A grouped by TMEM183A-low versus TMEM183A-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM183A→partner) and Y-score (partner→TMEM183A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	S100A7A →	+0.056	+5.643	<.001	.002	3	1
LARGE_INTESTINE	CFHR2 →	+0.038	+4.022	<.001	.006	3	1
LUNG_NSCLC_LUAD	SLC7A13 →	+0.006	+4.887	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

S100A7A by TMEM183A expression — BLOOD_Lymphoma

Explore this box plot interactively →