TMEM179

Across TCGA patient cohorts, TMEM179 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,102 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM179-associated proteins across cancer lineages are ZC2HC1A_S223, ZMYM3, and TLN1. Each is linked with TMEM179 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM179-to-partner and partner-to-TMEM179 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM179 versus ZC2HC1A_S223 in GBM, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM179→partner) and Y-score (partner→TMEM179) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZC2HC1A_S223 →	+0.801	+0.953	<.001	<.001	3	3
GBM	ZMYM3 →	+0.372	+1.114	<.001	<.001	3	3
GBM	TLN1 →	-0.297	-1.036	<.001	<.001	3	3
LSCC	TPM4 →	-0.369	-0.324	<.001	.004	3	3
LSCC	HIC1_S313 →	-0.488	-0.545	<.001	<.001	3	3
GBM	LIMS1 →	-0.399	-0.676	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,102 associations by consensus.

TMEM179 vs ZC2HC1A_S223 — GBM

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