TMEM151B

Across TCGA patient cohorts, TMEM151B protein abundance is significantly associated with the RNA expression of many other genes, with 1,190 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM151B-associated genes across cancer lineages are CRYBB2P1, CCDC134, and POLDIP3. Each is linked with TMEM151B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM151B-to-partner and partner-to-TMEM151B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM151B versus CRYBB2P1 in GBM, with a Pearson correlation of -0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM151B→partner) and Y-score (partner→TMEM151B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CRYBB2P1 →	-0.599	-0.922	<.001	.001	3	1
GBM	CCDC134 →	-0.578	-0.948	<.001	<.001	3	1
GBM	POLDIP3 →	-0.486	-1.021	.005	.008	3	1
GBM	SGSM3 →	-0.414	-1.139	.001	.004	3	1
GBM	TRMU →	-0.619	-0.807	<.001	.006	3	1
GBM	PMM1 →	-0.531	-1.067	.008	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,190 associations by consensus.

TMEM151B vs CRYBB2P1 — GBM

Explore this scatter interactively →