TMEM151A

Across TCGA patient cohorts, TMEM151A mutation is significantly associated with the RNA expression of many other genes, with 132 significant associations in total. COAD shows the largest number of these associations.

The most reproducible TMEM151A-associated genes across cancer lineages are MIR6894, TRIM51EP, and UBDP1. Each is linked with TMEM151A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM151A-to-partner and partner-to-TMEM151A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6894 grouped by TMEM151A-low versus TMEM151A-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM151A→partner) and Y-score (partner→TMEM151A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR6894 →	+0.516	+4.914	<.001	<.001	3	2
SKCM	TRIM51EP →	+0.027	+4.284	<.001	<.001	3	2
COAD	UBDP1 →	+0.099	+4.332	<.001	.006	3	2
COAD	ATP5MFP3 →	+0.160	+3.620	.002	.004	3	2
COAD	RPS7P13 →	+0.177	+3.325	<.001	.003	3	2
LUAD	FXYD6P3 →	+0.144	+5.584	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 132 associations by consensus.

MIR6894 by TMEM151A expression — BLCA

Explore this box plot interactively →