TMEM150C

Across TCGA patient cohorts, TMEM150C mutation is significantly associated with the RNA expression of many other genes, with 596 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM150C-associated genes across cancer lineages are ZNF519P4, DEFB104B, and OR7E97P. Each is linked with TMEM150C in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM150C-to-partner and partner-to-TMEM150C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF519P4 grouped by TMEM150C-low versus TMEM150C-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM150C→partner) and Y-score (partner→TMEM150C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ZNF519P4 →	+0.336	+4.282	<.001	.009	3	2
UCEC	DEFB104B →	+0.066	+4.475	<.001	.003	3	2
SKCM	OR7E97P →	+0.029	+5.900	<.001	<.001	3	2
SKCM	MIR7-2 →	+0.234	+4.614	<.001	.006	3	2
UCEC	VWA1 →	-0.946	-3.689	<.001	.001	3	1
UCEC	RCC1 →	+0.561	+3.218	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 596 associations by consensus.

ZNF519P4 by TMEM150C expression — SKCM

Explore this box plot interactively →