Q-omics provides the consensus-scored DEFB104B profile across patient tissues and cancer cell-line models. DEFB104B expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in UCS. Additionally, DEFB104B RNA expression shows 3,346 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight UCS, and ESCA as cancer lineages where DEFB104B shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for DEFB104B — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes DEFB104B survival associations across molecular data types. DEFB104B RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible DEFB104B RNA expression–survival associations across cancer types. High DEFB104B expression shows unfavorable associations in UCS, COAD, READ and BLCA, but favorable associations in CESC. The UCS Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCS as the clearest survival context for DEFB104B RNA expression.
This table shows molecular features associated with DEFB104B in patient tissues and cancer cell lines. In patient samples, DEFB104B shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set. In cancer cell lines, DEFB104B RNA and mutation anchors are most strongly linked to RNA-expression features, especially in UPPER_AERODIGESTIVE_TRACT.
