DEFB104B

Across TCGA patient cohorts, DEFB104B RNA expression is significantly associated with the go_rna of many other GO terms, with 587 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible DEFB104B-associated GO terms across cancer lineages are Establishment of skin barrier, Response to fungus, and Epidermal cell differentiation. Each is linked with DEFB104B in more than 2 cancer types. Because this analysis shows association rather than direction, both DEFB104B-to-partner and partner-to-DEFB104B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of skin barrier grouped by DEFB104B-low versus DEFB104B-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB104B→partner) and Y-score (partner→DEFB104B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Establishment of skin barrier →	+0.081	+0.123	<.001	<.001	3	3
ESCA	Response to fungus →	+0.065	+0.133	<.001	<.001	3	3
ESCA	Epidermal cell differentiation →	+0.070	+0.141	<.001	<.001	3	3
ESCA	Positive regulation of keratinocyte proliferation →	+0.153	+0.132	<.001	<.001	3	3
ESCA	Antimicrobial peptide production →	+0.225	+0.129	<.001	<.001	3	3
ESCA	Antibacterial peptide production →	+0.211	+0.136	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 587 associations by consensus.

Establishment of skin barrier by DEFB104B expression — ESCA

Explore this box plot interactively →