DEFB104B

Across TCGA pan-cancer cohorts, DEFB104B RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated DEFB104B data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher DEFB104B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DEFB104B expression acts as an unfavorable survival marker, although some lineages such as CESC show a favorable association.

UCS, READ, and COAD are the cancer types where DEFB104B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.104	0.688	<.001	108	view →
READ	DFS	Tertile	All	0.082	0.845	<.001	54	view →
COAD	DFS	Tertile	III,IV	0.028	0.668	<.001	54	view →
CESC	OS	Tertile	All	1.000	0.563	.021	36	view →
BLCA	DFS	Tertile	IV	0.090	0.469	.009	36	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DEFB104B–UCS (OS)

Open the UCS breakdown →