TMEM150A

Across TCGA cell cohorts, TMEM150A mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM150A-associated genes across cancer lineages are GSG1L2, GPR171, and TBC1D3. Each is linked with TMEM150A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM150A-to-partner and partner-to-TMEM150A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSG1L2 grouped by TMEM150A-low versus TMEM150A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM150A→partner) and Y-score (partner→TMEM150A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GSG1L2 →	+0.043	+4.969	<.001	.003	3	1
LARGE_INTESTINE	GPR171 →	+0.019	+4.273	<.001	.006	3	1
LARGE_INTESTINE	TBC1D3 →	+0.077	+4.273	<.001	.006	3	1
LARGE_INTESTINE	CCL18 →	+0.097	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

GSG1L2 by TMEM150A expression — BLOOD_Leukemia

Explore this box plot interactively →