TMEM150A

Across TCGA pan-cancer cohorts, TMEM150A RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of TMEM150A’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TMEM150A RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TMEM150A is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.

KIRC, COAD, and LIHC are the cancer types where TMEM150A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TMEM150A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	+0.601	<.001	12	view →
COAD	Female	All	+0.963	<.001	10	view →
LIHC	Female	II,III,IV	+1.040	<.001	9	view →
KICH	Female	All	−1.358	<.001	7	view →
LUSC	Female	All	−0.890	<.001	7	view →
BRCA	All	All	+0.175	.002	6	view →
THCA	All	All	+0.255	<.001	5	view →
STAD	Male	II,III,IV	+0.689	.004	4	view →
CHOL	All	All	+0.613	<.001	3	view →
HNSC	All	III,IV	+0.335	.026	2	view →
LUAD	Female	All	+0.332	.020	2	view →
PRAD	All	All	+0.200	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

TMEM150A–KIRC

Open the KIRC breakdown →