TMEM14C

Across TCGA patient cohorts, TMEM14C RNA expression is significantly associated with the protein abundance of many other proteins, with 8,372 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM14C-associated proteins across cancer lineages are WRNIP1, GNL1, and SKAP1. Each is linked with TMEM14C in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM14C-to-partner and partner-to-TMEM14C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM14C versus WRNIP1 in OV, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM14C→partner) and Y-score (partner→TMEM14C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	WRNIP1 →	+0.464	+0.577	.001	<.001	3	6
LSCC	GNL1 →	+0.285	+0.380	<.001	<.001	3	4
CCRCC	SKAP1 →	-0.618	-0.283	<.001	<.001	3	4
OV	NUP153 →	+0.268	+0.738	.003	<.001	3	3
LSCC	TRAF3IP3 →	-0.413	-0.388	<.001	<.001	3	3
BRCA	VAV1 →	-0.389	-0.402	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,372 associations by consensus.

TMEM14C vs WRNIP1 — OV

Explore this scatter interactively →