TMEM145

Across TCGA patient cohorts, TMEM145 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,695 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM145-associated proteins across cancer lineages are PAFAH1B3, RIPK3, and SUPT16H. Each is linked with TMEM145 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM145-to-partner and partner-to-TMEM145 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM145 versus PAFAH1B3 in BRCA, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM145→partner) and Y-score (partner→TMEM145) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PAFAH1B3 →	+0.454	+1.215	<.001	<.001	3	5
GBM	RIPK3 →	-0.446	-0.789	<.001	<.001	3	4
GBM	SUPT16H →	+0.428	+0.799	<.001	.001	3	4
GBM	DOCK8_S904 →	-0.597	-0.987	<.001	<.001	3	4
LSCC	EPS15 →	-0.239	-0.275	<.001	.001	3	4
LUAD	TOP1 →	+0.345	+0.300	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,695 associations by consensus.

TMEM145 vs PAFAH1B3 — BRCA

Explore this scatter interactively →