TMEM135

Across TCGA patient cohorts, TMEM135 RNA expression is significantly associated with the RNA expression of many other genes, with 20,593 significant associations in total. ACC shows the largest number of these associations.

The most reproducible TMEM135-associated genes across cancer lineages are LYSMD3, SPTY2D1, and MAGT1. Each is linked with TMEM135 in more than 33 cancer types. Because this analysis shows association rather than direction, both TMEM135-to-partner and partner-to-TMEM135 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM135 versus LYSMD3 in UVM, with a Pearson correlation of 0.83.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM135→partner) and Y-score (partner→TMEM135) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	LYSMD3 →	+1.662	+1.288	<.001	<.001	3	34
UVM	SPTY2D1 →	+1.102	+1.141	<.001	<.001	3	34
UVM	MAGT1 →	+1.547	+1.197	<.001	<.001	3	34
UVM	USO1 →	+1.846	+1.172	<.001	<.001	3	34
UVM	AASDHPPT →	+1.287	+1.197	<.001	<.001	3	34
UVM	CUL5 →	+1.642	+1.310	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,593 associations by consensus.

TMEM135 vs LYSMD3 — UVM

Explore this scatter interactively →