TMEM132A

Across TCGA patient cohorts, TMEM132A protein abundance is significantly associated with the RNA expression of many other genes, with 6,843 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM132A-associated genes across cancer lineages are CHPF, VPS37C, and KDM7A-DT. Each is linked with TMEM132A in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM132A-to-partner and partner-to-TMEM132A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM132A versus CHPF in HNSC, with a Pearson correlation of 0.20.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM132A→partner) and Y-score (partner→TMEM132A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CHPF →	+0.654	+0.279	.009	.003	3	4
HNSC	VPS37C →	+0.443	+0.356	<.001	<.001	3	4
UCEC	KDM7A-DT →	+0.705	+0.499	<.001	<.001	3	4
GBM	NCS1 →	+0.902	+0.346	<.001	<.001	3	3
UCEC	CYP2J2 →	+1.334	+0.709	<.001	<.001	3	3
BRCA	ZFAND4 →	-0.589	-0.305	.003	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,843 associations by consensus.

TMEM132A vs CHPF — HNSC

Explore this scatter interactively →