TMEM131L

Across TCGA patient cohorts, TMEM131L protein abundance is significantly associated with the RNA expression of many other genes, with 2,048 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TMEM131L-associated genes across cancer lineages are NEK11, ERN2, and CDKN3. Each is linked with TMEM131L in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM131L-to-partner and partner-to-TMEM131L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM131L versus NEK11 in OV, with a Pearson correlation of -0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM131L→partner) and Y-score (partner→TMEM131L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NEK11 →	-0.684	-0.587	.003	.001	3	2
LUAD	ERN2 →	-2.550	-0.445	<.001	.003	3	2
LUAD	CDKN3 →	+1.332	+0.374	<.001	.004	3	2
CCRCC	TMEM26 →	-0.529	-0.822	.004	.007	3	2
OV	TEX11 →	+0.649	+0.827	.001	.006	3	1
OV	CRY2 →	+0.539	+0.495	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,048 associations by consensus.

TMEM131L vs NEK11 — OV

Explore this scatter interactively →