TMCO1

Across TCGA patient cohorts, TMCO1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,091 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMCO1-associated proteins across cancer lineages are SCAMP3, DCAF8, and BROX. Each is linked with TMCO1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMCO1-to-partner and partner-to-TMCO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMCO1 versus SCAMP3 in CCRCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMCO1→partner) and Y-score (partner→TMCO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SCAMP3 →	+0.380	+0.388	<.001	<.001	3	6
OV	DCAF8 →	+0.243	+0.421	.004	.004	3	5
LSCC	BROX →	+0.449	+0.482	<.001	.001	3	5
CCRCC	CERS2 →	+0.431	+0.427	.001	<.001	3	4
COAD	FDPS →	+0.383	+0.448	<.001	.001	3	4
COAD	RNASEL →	+0.311	+0.532	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,091 associations by consensus.

TMCO1 vs SCAMP3 — CCRCC

Explore this scatter interactively →