TM4SF20

Across TCGA patient cohorts, TM4SF20 protein abundance is significantly associated with the RNA expression of many other genes, with 126 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TM4SF20-associated genes across cancer lineages are TMEM54, SLC39A5, and TMEM140. Each is linked with TM4SF20 in more than 1 cancer types. Because this analysis shows association rather than direction, both TM4SF20-to-partner and partner-to-TM4SF20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TM4SF20 versus TMEM54 in PDAC, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM4SF20→partner) and Y-score (partner→TM4SF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TMEM54 →	+1.147	+1.685	<.001	.006	3	1
PDAC	SLC39A5 →	+2.031	+1.685	<.001	.006	3	1
PDAC	TMEM140 →	+0.976	+1.685	.007	.006	3	1
PDAC	MAJIN →	+0.570	+1.729	.009	.009	3	1
PDAC	FPR2 →	+2.142	+1.684	.003	.006	3	1
PDAC	HSD11B2 →	+1.686	+1.685	.009	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 126 associations by consensus.

TM4SF20 vs TMEM54 — PDAC

Explore this scatter interactively →