TM4SF20

Across TCGA patient cohorts, TM4SF20 mutation is significantly associated with the RNA expression of many other genes, with 1,590 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TM4SF20-associated genes across cancer lineages are OR5I1, MIR4262, and RNU1-14P. Each is linked with TM4SF20 in more than 1 cancer types. Because this analysis shows association rather than direction, both TM4SF20-to-partner and partner-to-TM4SF20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5I1 grouped by TM4SF20-low versus TM4SF20-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TM4SF20→partner) and Y-score (partner→TM4SF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR5I1 →	+0.032	+3.489	<.001	.003	3	2
BRCA	MIR4262 →	+0.734	+7.731	<.001	.009	3	2
LUSC	RNU1-14P →	+0.684	+7.924	<.001	.008	3	2
LUSC	RNU6-776P →	+0.863	+7.924	<.001	.008	3	2
LUSC	RNU6-294P →	+1.508	+7.924	<.001	.008	3	2
LUSC	MIR489 →	+0.973	+7.924	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,590 associations by consensus.

OR5I1 by TM4SF20 expression — UCEC

Explore this box plot interactively →