TM4SF20

Across TCGA cell cohorts, TM4SF20 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,108 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TM4SF20-associated GO terms across cancer lineages are Serotonin biosynthetic process, Indole-containing compound biosynthetic process, and Primary alcohol metabolic process. Each is linked with TM4SF20 in more than 5 cancer types. Because this analysis shows association rather than direction, both TM4SF20-to-partner and partner-to-TM4SF20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Serotonin biosynthetic process grouped by TM4SF20-low versus TM4SF20-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TM4SF20→partner) and Y-score (partner→TM4SF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Serotonin biosynthetic process →	+1.752	+1.679	<.001	<.001	3	6
LARGE_INTESTINE	Indole-containing compound biosynthetic process →	+1.862	+1.567	<.001	<.001	3	6
KIDNEY	Primary alcohol metabolic process →	+0.108	+0.046	.002	.005	3	5
LARGE_INTESTINE	Fatty acid metabolic process →	+0.053	+1.538	<.001	<.001	3	5
LARGE_INTESTINE	Sesquiterpenoid metabolic process →	+0.305	+1.310	<.001	<.001	3	5
BLOOD_Leukemia	Nucleoside triphosphate biosynthetic process →	+0.051	+0.014	.004	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,108 associations by consensus.

Serotonin biosynthetic process by TM4SF20 expression — LARGE_INTESTINE

Explore this box plot interactively →