TLE5

Across TCGA cell cohorts, TLE5 RNA expression is significantly associated with the RNA expression of many other genes, with 11,510 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TLE5-associated genes across cancer lineages are CACTIN, NDUFS7, and CSNK1G2. Each is linked with TLE5 in more than 14 cancer types. Because this analysis shows association rather than direction, both TLE5-to-partner and partner-to-TLE5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TLE5 versus CACTIN in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.59.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TLE5→partner) and Y-score (partner→TLE5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	CACTIN →	+1.028	+1.258	<.001	<.001	3	15
OESOPHAGUS	NDUFS7 →	+1.230	+0.847	.001	<.001	3	15
LARGE_INTESTINE	CSNK1G2 →	+1.070	+0.895	<.001	<.001	3	15
LARGE_INTESTINE	GNA11 →	+1.196	+1.028	<.001	<.001	3	15
BLOOD_Lymphoma	TCF3 →	+1.995	+0.918	<.001	<.001	3	15
CNS	TBC1D10B →	+0.827	+0.829	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,510 associations by consensus.

TLE5 vs CACTIN — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →